The aim of current study is review of Myocardial infarction with non-obstructive coronary arteries (MINOCA) diagnostic and treatment strategies.
Material and Methods: This study used a comprehensive structured systematic approach that included a methodical literature search.
Results: Varies observational studies shows that a sizeable proportion of myocardial infarctions (MI), ranging between 1–14%, occur in the absence of obstructive (>50% stenosis) coronary artery disease. The potential mechanisms responsible for MI in MINOCA patients are structural myocardial dysfunction, coronary artery spasm and trombophilia disorders. Identifying treatable causes of MINOCA is fundamental to its clinical assessment as these may have prognostic implications and may impact on its guarded prognosis.
Conclusion: Myocardial infarction with non-obstructive coronary arteries is identified using a working diagnosis made following coronary angiography in the assessment of patients with an AMI. In patients in whom no specific cause is found, further studies are warranted to assess the most effective treatment.