Clinical and physiological evaluation of dexmedetomidine, xylazine and triflupromazine as pre-anaesthetics with propofol-isoflurane anaesthesia for various surgeries in dogs
Arunkumar S, Dilipkumar D and BV Shivaprakash
The research was conducted in 18 clinical cases presented to TVCC, Bidar. Animals were randomly divided into three groups viz., Group-I, Group-II and Group-III consisting of six animals in each group. Animals of all the groups were atropinised (0.045mg/kg) intramuscularly. Dogs in Group-I received dexmedetomidine (10µg/kg) intravenously. In the Group-II, xylazine (1mg/kg) was administered intravenously. In the Group-III, triflupromazine (1mg/kg) was administered intravenously. After ten minutes anesthesia was induced by propofol (3mg/kg) intravenously to each animal of all the groups. Maintenance of anesthesia was done by isoflurane in three groups. Anaesthetic combinations were evaluated by clinical and physiological observations. The induction and recovery were smooth and uneventful in three groups. Onset of sedation and induction time were narrowly quicker in Group-I. Excellent muscle relaxation and good analgesia were observed in group-II dogs. Physiological parameters fluctuated within the normal limits. Three anesthetic protocols in the present study provided satisfactory surgical plane of anesthesia in dogs.
How to cite this article:
Arunkumar S, Dilipkumar D, BV Shivaprakash. Clinical and physiological evaluation of dexmedetomidine, xylazine and triflupromazine as pre-anaesthetics with propofol-isoflurane anaesthesia for various surgeries in dogs. Pharma Innovation 2017;6(8):100-105.