Vol. 6, Issue 7 (2017)

Methods: The Strobilanthes ciliatus plant powder was extracted with ethanol by cold maceration technique. Primary and secondary metabolites in the plant extract were identified by means of phytochemical screening or specific tests. The in-vivo analgesic activity was subsequently assessed by tail-clip method.

Results: The phytochemical screening showed the presence of flavanoids, phenolic compounds, tannins, steroids, glycosides and triterpenoids. The in vivo study revealed that the extract has analgesic activity

Conclusion: The present study provides a biochemical rationale by which Strobilanthes ciliatus Nees elicited effect on pain. Analgesic property of plant extract at a dose of 100mg/kg was evaluated against the standard drug Diclofenac at a dose of 20mg/100g using tail clip models of pain. The extract of Strobilanthes ciliatus Nees showed more significant analgesic activity (p<0.001) as compared to standard drug.