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Vol. 6, Issue 7 (2017)

Evaluation of analgesic activity of ethanolic extract of Strobilanthes ciliatus Nees

Author(s):
Prof. Dr. Mathew George, Prof. Dr. Lincy Joseph and Sony S
Abstract:
Objective: The present study was aimed to investigate the phytochemical analysis and analgesic activity of ethanolic extract of stem of Strobilanthes ciliatus Nees.
Methods: The Strobilanthes ciliatus plant powder was extracted with ethanol by cold maceration technique. Primary and secondary metabolites in the plant extract were identified by means of phytochemical screening or specific tests. The in-vivo analgesic activity was subsequently assessed by tail-clip method.
Results: The phytochemical screening showed the presence of flavanoids, phenolic compounds, tannins, steroids, glycosides and triterpenoids. The in vivo study revealed that the extract has analgesic activity
Conclusion: The present study provides a biochemical rationale by which Strobilanthes ciliatus Nees elicited effect on pain. Analgesic property of plant extract at a dose of 100mg/kg was evaluated against the standard drug Diclofenac at a dose of 20mg/100g using tail clip models of pain. The extract of Strobilanthes ciliatus Nees showed more significant analgesic activity (p<0.001) as compared to standard drug.
Pages: 326-328  |  630 Views  30 Downloads
How to cite this article:
Prof. Dr. Mathew George, Prof. Dr. Lincy Joseph, Sony S. Evaluation of analgesic activity of ethanolic extract of Strobilanthes ciliatus Nees. Pharma Innovation 2017;6(7):326-328.
The Pharma Innovation Journal