Vol. 6, Issue 7 (2017)

Author(s):
Umesh Chandra, Archana Dhyani And Dr. Divya Juyal

Abstract:
Floating microsponges are an approach to prolong gastric residence time, there by targeting site-specific drug release in the upper GIT for local or systemic effect. Gastro retentive dosage forms (GRDFs) are being used from a very long time to improve therapy with several essential drugs. Floating microsponge greatly improves the therapy of stomach by releasing the drug locally and thus used for drug targeting at particular organ. This can be sustained over a longer duration of time. Floating drug delivery (FDDs) permit prolonged and continuous release of the drug to the upper part of Gastro intestinal tract (GIT) and this expressively extend the duration of drug release and improve bioavailability of drugs that have narrow therapeutic window, by this technique dosing frequency and patient compliance is increased. The purpose of this paper is to briefly describe the floating microsponge drug delivery (FMDD), factors related to Floating Drug Delivery, its advantages disadvantages, and emphasis is given over its significance over conventional form of drug deliveries.