Vol. 6, Issue 7 (2017)

Author(s):
Vivek Kumar, Pawan Jalwal And Surender Singh

Abstract:
The goal of this research is to formulate dispersible tablet of Sultamicillin for kids. It is a comfortable formulation for infants, toddlers and pre-school children. Dispersible tablets usually disintegrate within three minutes when put into water or a small amount of breast milk. Sultamicillin is a mutual prodrug of Ampicillin and Sulbactam. Sulbactam is β-lactamase inhibitor which in combination with Ampicillin increases the antibacterial activity of Ampicillin. The aim was achieved by using super disintegrant like crosscarmellose sodium. Due to less disintegration time, less dispersion time and having good taste, F3 was the final formulation. It was concluded that this was the better combination of ingredients for patient compliance and good taste.