Vol. 6, Issue 6 (2017)
Evaluation of the nitric oxide scavenging potential of Harungana madagascariensis Lam ex poir (Hypericaceae) fruits oil
Ozadheoghene Eriarie Afieroho and Mercy Chinyeaka Afieroho
This study investigated the in vitro nitric oxide scavenging activity of the oil extract from the non-utilised fruits of Harungana madagascariensis a plant widely used in ethno-medicine. The H. madagascariensis fruits oil (HMO) was obtained by de-fatting the chloroform extract of the air-dried fruits with n-hexane and the n-hexane extract further separated on a normal phase silica gel column to afford the HMO. Nitric oxide (NO) scavenging assay was done using standard spectrophotometric method. The HMO exhibited a concentration dependent NO scavenging potential comparable (p=0.05) to that of Vitamin A at 50 µg/ml. Compared to the reference antioxidants used for comparison the trend in NO activity inhibition IC50 (µg/ml) of : HMO(IC50=214.1)
How to cite this article:
Ozadheoghene Eriarie Afieroho, Mercy Chinyeaka Afieroho. Evaluation of the nitric oxide scavenging potential of <em>Harungana madagascariensis </em>Lam ex poir (Hypericaceae)<em> </em>fruits oil. Pharma Innovation 2017;6(6):171-173.