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Vol. 6, Issue 6 (2017)

Evaluation of the nitric oxide scavenging potential of Harungana madagascariensis Lam ex poir (Hypericaceae) fruits oil

Author(s):
Ozadheoghene Eriarie Afieroho and Mercy Chinyeaka Afieroho
Abstract:
This study investigated the in vitro nitric oxide scavenging activity of the oil extract from the non-utilised fruits of Harungana madagascariensis a plant widely used in ethno-medicine. The H. madagascariensis fruits oil (HMO) was obtained by de-fatting the chloroform extract of the air-dried fruits with n-hexane and the n-hexane extract further separated on a normal phase silica gel column to afford the HMO. Nitric oxide (NO) scavenging assay was done using standard spectrophotometric method. The HMO exhibited a concentration dependent NO scavenging potential comparable (p=0.05) to that of Vitamin A at 50 µg/ml. Compared to the reference antioxidants used for comparison the trend in NO activity inhibition IC50 (µg/ml) of : HMO(IC50=214.1)
Pages: 171-173  |  618 Views  16 Downloads
How to cite this article:
Ozadheoghene Eriarie Afieroho, Mercy Chinyeaka Afieroho. Evaluation of the nitric oxide scavenging potential of <em>Harungana madagascariensis </em>Lam ex poir (Hypericaceae)<em> </em>fruits oil. Pharma Innovation 2017;6(6):171-173.
The Pharma Innovation Journal