Vol. 6, Issue 6 (2017)

Author(s):
Priyanka Jaiswal and Padma Kumar

Abstract:
Exposure of pathogenic microorganisms to the newly invented different kinds of drugs, results in the increased in antibiotic resistant strains of pathogenic organisms. Thus, a variety of new antimicrobial agents are needed to combat the decreasing efficacy of existing antibiotics. In the present work effort in this direction was carried out to assess the antimicrobial activity of Saraca asoca bark extracts against some multidrug resistant pathogenic bacteria. Water, methanol, petroleum ether, flavonoids, alkaloids and steroids extracts were examined for antimicrobial activity using ‘Disc Diffusion Assay’. Minimum inhibitory concentration, Minimum bactericidal concentration, Total activity and Activity index were taken up and statistically were analyzed. Maximum zone of inhibition observed for bound flavonoids and methanolic extracts. The lowest MIC value of bound flavonoids 0.078 mg/ml was recorded against Pseudomonas aeruginosa whereas, lowest MBC observed was 0.156 mg/ml, indicating significant antimicrobial potential of test extracts. The results of the above study revealed that the bound flavonoid and methanolic extracts were exhibited significant antibacterial activity which might be helpful in preventing the progress of various diseases and can be used in an alternative system of medicine.