Vol. 6, Issue 5 (2017)

Author(s):
Preetha Nandabalan and Suguna Bai Arone

Abstract:
The most challenging factor after diagnosis of end stage liver disease like hepatic encephalopathy is choosing the definitvie drug to improve the neuropsychometric performance of the patient. This study aims at analyzing the combined effect of Synbiotic and L-ornithine L-aspartate (LOLA) in improving brain function among patients admitted with covert hepatic encephalopathy. Methods: 40 cirrhotic patients with impaired psychometric performance were enrolled and randomized into control and study group receiving standard therapy and study drugs along with standard therapy respectively. Patients were evaluated using neuropsychometric tests on day 0, 7 and 14. Results were analysed statistically. In conclusion there is significant improvement in neurological function in patients receiving Synbiotics in combination with LOLA.