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Vol. 6, Issue 5 (2017)

In-vitro MABA anti-tuberculosis assay of Eclipta Alba (L.) Hassk whole plant

Author(s):
Ramaiah Maddi, Devilal K, Satish Babu and Harika P
Abstract:
Tribal community are using traditional knowledge system to cure various diseases. They use natural source of drugs through trial and error method and the process is experienced over hundreds of years, this says that the medicinal plant shave been in the focus as lifesaving drugs right from the beginning of the human civilization. Eclipta Alba (L.) Hassk one such plant which has a strong research support of its use in biological activities such as antihepatotoxic, ophthalmic, digestive, carminative, aphrodisiac, anti-inflammatory and antimycobacterial actions etc. E. Alba has shown a wide variety of medicinal importance, we have here tested in-vitro anti-tubercular activity by using Micro-plate Alamar Blue Assay (MABA) method. Ethanolic and aqueous extracts were prepared for evaluation of anti-tubercular activity against Mycobacterium tuberculosis. The result of the in-vitro anti-tubercular activity of the crude extracts at concentrations of 1 mg/mL, 25 mg/mL, 50mg/mL and 100mg/mL revealed that both the extracts (aqueous and ethanolic) inhibited the growth of the bacterium at MIC of 1 mg/ml.
Pages: 103-105  |  919 Views  28 Downloads
How to cite this article:
Ramaiah Maddi, Devilal K, Satish Babu, Harika P. In-vitro MABA anti-tuberculosis assay of Eclipta Alba (L.) Hassk whole plant. Pharma Innovation 2017;6(5):103-105.
The Pharma Innovation Journal