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Vol. 6, Issue 5 (2017)

Ciprofloxacin metal complexes and their biological activities: A review

Author(s):
Mausin Khan, Mahtab Ali and Divya Juyal
Abstract:
Ciprofloxacin is a derivative of quinolone. Quinolones possesses antibacterial activity and they are structurally related to Nalidixic acid. Various modification has been done in quinolone moiety to enhance antibacterial activity and reduce resistance. On chelation, quinolones acts as unidentate, bidentate and bridging ligand. Metal ions play an important role in biological activity with quinolones. Various transition metals are used as chelating agent such as Ni2+, Co2+, Ca2+, Zn2+, Ag2+, Au2+, Mn2+, Mg2+, Fe2+ etc.
Pages: 73-78  |  821 Views  21 Downloads
How to cite this article:
Mausin Khan, Mahtab Ali, Divya Juyal. Ciprofloxacin metal complexes and their biological activities: A review. Pharma Innovation 2017;6(5):73-78.
The Pharma Innovation Journal