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Vol. 6, Issue 12 (2017)

Effects of comprehensive treatment with quercetin administration on biochemical blood parameters and pro-and anti-inflammatory cytokines in nonalcoholic fatty liver disease patients

Author(s):
VP Prysyazhnyuk and OI Voloshyn
Abstract:
The effect of additional administration of Quercetin to the basic treatment on the clinical course, biochemical parameters, pro- and anti-inflamatory cytokines plasma levels in nonalcoholic fatty liver disease patients was investigated. Indicators that reflect the processes of cytolysis and metabolic intoxication within two weeks of treatment were more effectively improved in nonalcoholic fatty liver disease patients, who in addition to standard treatment received Quercetin. The decrease in the concentration of total cholesterol by 16,7% (p = 0,03) and triacylglycerols – by 33,3% (p = 0,002) was found in patients of the main group. Patients who additionally to basic treatment were prescribed Quercetin after two weeks of treatment also noted a significant reduction in the contents of tumor necrosis factor-α by 39,8% (p = 0,03) and atrial natriuretic propeptide in 2,07 times (p = 0,04) in the blood, indicating its anti-inflammatory and cardioprotective properties, and substantiates the feasibility of its use as a multifaceted medication in nonalcoholic fatty liver disease patients.
Pages: 386-389  |  1399 Views  12 Downloads
How to cite this article:
VP Prysyazhnyuk, OI Voloshyn. Effects of comprehensive treatment with quercetin administration on biochemical blood parameters and pro-and anti-inflammatory cytokines in nonalcoholic fatty liver disease patients. Pharma Innovation 2017;6(12):386-389.
The Pharma Innovation Journal