Vol. 6, Issue 11 (2017)

Author(s):
Haritma Chopra

Abstract:

Methionine is a sulphur containing essential amino acid and cannot be synthesised in living beings. In deficiency state of methionine, the formation of creatinine would be reduced giving a false impression of depressed kidney function. Therefore, a comprehensive kinetic study was carried out to study its interaction with metal ions Co (II) and Cu(II). Rate constants corresponding to the binding steps, outer sphere complex formation reaction (K_os), rate constant of water exchange (k_o) were computed. The proposed mechanism is supported by the computation of activation parameters corresponding to stepwise rate constants.