Vol. 6, Issue 11 (2017)

Author(s):
Supriya Pathak, Manoj Kumar Mishra, Md. Amman Maqbool, Adarsh Kesharwani and Anuradha Kesharwani

Abstract:
Carrier erythrocytes have been evaluated in thousands of drug administration in humans proving safety and efficacy of the treatments. Carrier erythrocytes, resealed erythrocytes loaded by a drug or other therapeutic agents. Erythrocytes mediated drug delivery has been reported with therapeutic enzymes and antiviral agents to maximize therapeutic performance, reduce the side effects, as circulating depots for controlled drug release, drug targeting, treatment of parasitic diseases, hepatic tumors, removal of toxic agents etc. Resealed Erythrocytes are biocompatible, biodegradable, possess long circulation half-life and can be loaded with variety of active drug substances.