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Vol. 6, Issue 10 (2017)

Secondary long QT syndrome: Prevention and management

Sergiy Fedorov
Long QT syndrome is characterized by prolongation of the corrected QT (QTc) interval on the surface electrocardiogram and is associated with precipitation of torsade de pointes, a polymorphic ventricular tachycardia that may cause sudden death. The prevalence of Long QT syndrome is close to 1/3000-1/5000. The QT interval duration is physiologically variable: the QTc is calculated using the Bazett’s formula. Acquired long QT syndrome is an important issue for clinicians and a significant public health problem concerning the large number of drugs with this adverse effect with a potentially fatal outcome, the large number of patients exposed to these drugs, and our inability to predict the risk for a given individual. In this paper, we focus on mechanisms underlying QT prolongation, risk factors for torsades de pointes and describe the short- and long-term treatment of acquired long QT syndrome.
Pages: 313-314  |  937 Views  74 Downloads

The Pharma Innovation Journal
How to cite this article:
Sergiy Fedorov. Secondary long QT syndrome: Prevention and management. Pharma Innovation 2017;6(10):313-314.

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