Vol. 5, Issue 7 (2016)

Author(s):
Tamara Turlyun and Natalya Pertseva

Abstract:
The issue of studying features of endothelial dysfunction of vessels in patients with arterial hypertension (AH) and different cardiovascular risk remains essential. While studying two groups of patients with moderate and a high risk for developing cardiovascular conditions it has been determined that, body mass index (BMI) increased significantly more expressed in the group with AH with the high risk for cardiovascular conditions (p<0.01 in comparison with the first group). Ratio WC/HC and WC/height exceeds the recommended indices, which confirms the presence of overweight in the main part of the studied patients in general. DBP in the second group has been reliably higher than the indices of the first group (p<0.001). The average value of TC exceeds the recommended values, level of high-density lipoproteins (HDL) has been confirmed to be different in both groups at the beginning of the research and it has been higher in the first group (Ñ€<0.05). In the group of the high risk, irrefutable increase in endothelin-1 (ET-1) and vWF (von Willebrand factor) has been observed compared to indices in the group with a moderate risk (Ñ€<0.001), which testifies to more expressed vasoconstriction and progressive blood clots in vessels.