Vol. 5, Issue 7 (2016)
Development and Evaluation of Oral Fast Dissolving Tablets of Lornoxicam using Superdisintegrants - A Comparative Study
Jitender Mor, Parveen Chauhan, Pawan Jalwal
The concept of fast dissolving drug delivery system emerged from the desire to provide patient with more convenient means of taking their medication. It is difficult for many patients to swallow tablets and hard gelatin capsules. The main objective of the study is to develop reproducible formulation of fast dissolving tablets of Lornoxicam already used therapeutic molecule to enhance effectiveness, and to avoid side effects (gastric irritation) of the drug. Different batches of tablets were prepared by direct compression method using different concentration of superdisintegrants like Plantago ovata, Cross povidone, Cross carmellose sodium, Sodium starch glycollate. Before compression preformulation studies were done which includes characterization of blend and physical compatibility studies with excipients. Effect of change in superdisintegrant and there concentration on the formulation was studied. Final batches were compared for superiority of superdisintegrants in the formulation of FDT of Lornoxicam.b
How to cite this article:
Jitender Mor, Parveen Chauhan, Pawan Jalwal. Development and Evaluation of Oral Fast Dissolving Tablets of Lornoxicam using Superdisintegrants - A Comparative Study. Pharma Innovation 2016;5(7):01-07.