Could really systemic inflammatory markers be predictors of COPD Progression
BO Basina, GV Kondrateva
Inflammatory biomarkers are considered by modern researchers as one of the best markers of effectiveness of inhaled corticosteroids (ICS) at patients with COPD, but there are a few studies about their prediction opportunity for COPD progression. The study is devoted to study of the diagnostic value of some markers of systemic inflammation (CRP, fibrinogen, MMP-2 and -9, hyaluronic acid (HA) at patients with COPD, there role as predictors of COPD progression. It was determined that determination of dynamic levels of such marker of systemic inflammation as MMP-2, CRP, HA can be used as parameters for further evaluation of the clinical stability of patients during their long-term follow-up. Significant decreasing of inflammatory markers shows the adequacy of anti-inflammatory therapy of patients with COPD regardless of changes in lung function dynamic disorders.
How to cite this article:
BO Basina, GV Kondrateva. Could really systemic inflammatory markers be predictors of COPD Progression. Pharma Innovation 2016;5(5):91-93.