study cytological features and different patterns of granulomatous inflammation in lymph node aspirates.
Material and method: The present prospective and retrospective study is carried out in 536 cases of clinical diagnosed lymphadenopathy for fine needle aspiration cytology in the department of pathology, Krishna Institute of Medical Sciences University, Karad, during the period of May 2005 to April 2008 (retrospective) and May 2008 to December 2010 (prospective).
Result: In our study of 122 granulomatous cases, 106 given as tuberculous lymphadenitis out of which 17 cases underwent for histopathological examination and 16 reported as tuberculous lymphadenitis except one which is given as reactive lymph node. Therefore % of false negative cases is 5.88%.In remaining eight granulomatous lesions, we could not find any causative agents like organisms, inclusion bodies or fungi with routine stain and even with special stains. These cases were subjected for lymph node biopsy and histopathological study.
Conclusion: In all these cases, careful clinical history like HIV positive status, H/O vaccination, cat bite and scratches and radiological investigation in case of sarcoidosis like chest X-ray and MRI findings and thorough clinical examination helped us to arrive at the diagnosis. The clinical history is far most important to arrive at particular diagnosis in some uncommon cases of lymphadenopathy. Thus to conclude, Fine Needle Aspiration Cytology is likely to be more successful is close knit setup with constant interaction and feedback between clinicians and pathologists.