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Vol. 4, Issue 7 (2015)

Histopathological examination of placenta in second and third trimester of pregnancy in various clinical settings

Author(s):
Dr. SR Upadhye and Dr. Dhirjkumar B Shukla
Abstract:
Material and method: 144 cases were obtained in a hospital based prospective study within a period of 2 years from May 2009 to April 2011 for descriptive and cross-sectional study. In 81.25% of cases the age group was 21-30 years, majority (73.6%) of cases were in the third trimester of pregnancy.
Results: Fetal disorders formed the major (48.6%) clinical presentation followed by maternal (39.6%) and placental disorders (11.8%). Overlapping of clinical features was observed. Fetal disorders included prematurity (43%), IUD (35.3%), fetal distress (12.4%), IUGR (11.7%), twin pregnancy (6.9%), and erythroblastosis fetalis (0.7%). There were 17 cases of disorders of placental disc and umbilical cord, which included abnormal cord insertion (35.3%), cord twists (23.6%), single umbilical artery (17.6%), placenta accreta and succenturate lobe (17.6%) and chorangioma (5.9%).Overall histopathological diagnoses included uteroplacental insufficiency (55.6%), chorioamnionitis and villitis (33.3%), chorangiosis (13.8%), lesions of cord (9%), amnion nodosum (2.8%), lesions of placental disc (2.8%) and erythroblastosis fetalis (0.7%). Overlapping of one or more features was observed.
Conclusion: Placental examination assists in timely management of mother and fetus. Diagnosis of placental lesions helps to improve the outcome of pregnancy. Hence placental pathology should be a routine component of obstetric and neonatal care.
Pages: 149-153  |  527 Views  100 Downloads


The Pharma Innovation Journal
How to cite this article:
Dr. SR Upadhye, Dr. Dhirjkumar B Shukla. Histopathological examination of placenta in second and third trimester of pregnancy in various clinical settings. Pharma Innovation 2015;4(7):149-153.

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