Abstract:Aims and objectives:
1. To study the cytomorphological changes in oral cavity of different pathological lesions of chronic tobacco chewers in the rural population. 2. Assess the significance of the oral scrape cytology in oral mucosa of tobacco chewers.
Materials and methods: A total number of 100 patients with oral mucosal lesions with Gutkha chewing habit were studied. The distribution of patients included both males and females of all age groups and socioeconomic status compared with the controls comprising of 50 persons with no history of tobacco chewing.
Results: On cytological diagnosis, 53% lesions were inflammatory followed by 30% dysplastic and 12% were positive/suspicious for malignant cells. Out of 16 clinically suspected carcinoma cases, 12 came out positive on cytology and 13 were confirmed on histopathology.
Conclusion: This study supports the hypothesis that tobacco chewing elevates the risk of oral submucous fibrosis, leukoplakia and cancer. Oral scrape cytology has been found to be very helpful to detect precancer and cancerous conditions; hence we recommend the use of oral scrape cytology as a screening tool in all suspicious intraoral lesions for rapid diagnosis.