Vol. 3, Issue 6 (2014)

Author(s):
Anoop Agnihotri, Vijender Singh

Abstract:
In the present study a solid pharmaceutical dosage form (Tablet) was prepared using hydro-alcoholic extracts of Cassia fistula (Stem Bark), Tamarindus indica (Stem Bark) and Tectona grandis (Heart Wood) by the direct compression method.  Various combinations of dried granules of powdered extracts were prepared and characterized on the basis of pre-formulation parameters like angle of repose, loose bulk density, tapped bulk density, loss on drying, compressibility index and Hausner ratio etc. Pre-formulation study of the granules showed that all the evaluated parameters were within the acceptable limits. The tablets were evaluated for various parameters like Hardness, Friability, Disintegration time etc. Among six formulations prepared (F1 to F6), F3 showed appreciable results.