Vol. 3, Issue 3 (2014)

Author(s):
Meenakshi Chaudhary, R. K. Srivastava, Veena Ghalaut

Abstract:
The study was done to find out the effect of Liraglutide on formalin induced tonic pain in obese rabbits. Rabbits were made obese by giving HFD (High fat diet) for 10 weeks. Tonic pain was induced with 5% formalin and it was observed that obese rabbits showed a significantly lesser pain score as compared to normal rabbits. Liraglutide     (7μg/kg s.c.) was then given to both the group of rabbits for 3 weeks and it was observed that Liraglutide, though produced a significant decrease in body weight, but decrease in tonic pain scores was not significant in obese rabbits.