Vol. 3, Issue 2 (2014)

Author(s):
Jaroslava Vandzhura

Abstract:
The article presents data on the effect of carnitine containing drug cardonat on endothelial dysfunction and pathological stroma restructuring of myocardium in patients after myocardial infarction within 6 months of medical rehabilitation.
Combination of cardonat with standard therapy promotes correction of collagen metabolism abnormalities, namely reducing the synthesis of abnormal collagen.
Also, this drug combination improves endothelial function: it increases the synthesis of nitric oxide, reduces the level of active nitrogen radicals. This generally provides a favourable clinical course of postinfarction period and reduces the pathological left ventricle remodelling.