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Vol. 2, Issue 6 (2013)

Identification of Candida Sp. and their Antifungal sensitivity from patients at a tertiary care hospital

Abhijita Mohapatra, Rajesh Kumar Lenka
Objective: In this analysis, we evaluated the prevalence of Candida Sp. in patients visiting the department of medicine and gynecology. Additionally, we assessed the known Candida sp.'s antibiotic sensitivity profiles.
Methods: From January 2011 to February 2012, this prospective, cross-sectional study was undertaken at the IMS and SUM hospital and included the infection-causing organisms. Specific traditional media techniques helped to confirm the existence of species difference. Using disc diffusion techniques, the antifungal susceptibility of distant Candida species has been assessed.
Results: e bulk of the 219 Candida isolates were from the departments of medicine (59; 26.9%) and gynaecology (78; 35.6%). Additionally, 75 (34.2%) of the samples were from married women, whereas 144 (65.8%) were from unmarried females. Candida glabrata 30(13.69%), Candida tropicalis 26(11.87%), Candida krusei 17(7.76%), Candida parapsilosis 12(5.47%), Candida dubliniensis 3(1.37%), and Candida lusitaniae 3(1.37) were the next most prevalent species after Candida albicans, which had 128 (58.45%) of the total. Amphotericin B has proven to be the least effective against all isolates, with a susceptibility charge of 213 (97.26%). When compared to fluconazole 32 (14.61%), voriconazole 40 (18.26%) showed the highest level of resistance.
Conclusion: Amphotericin B is the most effective antifungal for skin infections, according to this study. Candida species have shown resistant to numerous antifungals.
Pages: 67-72  |  211 Views  103 Downloads

The Pharma Innovation Journal
How to cite this article:
Abhijita Mohapatra, Rajesh Kumar Lenka. Identification of Candida Sp. and their Antifungal sensitivity from patients at a tertiary care hospital. Pharma Innovation 2013;2(6):67-72.

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