Synthesis and Characterisation of 3-Acetylindole Derivatives and Evaluation of Their Anti-Inflammatory and Anti-Microbial Activity
Author(s):
Loveleen Verma *, Dr. Sharad Wakode
Abstract:
A series of 3-Acetylindole derivatives were synthesised by a three step process by reacting 3-acetylindole and aromatic aldehydes in the first step. The purity and structure confirmation of the synthesised compounds were done by TLC and 1H-NMR. The compounds were evaluated for anti-microbial and anti-inflammatory activity. The test compound LV-5 showed highest anti-inflammatory activity and the test compounds LV-5, LV-6 and LV-8 showed highest anti-microbial activity.
How to cite this article:
Loveleen Verma *, Dr. Sharad Wakode. Synthesis and Characterisation of 3-Acetylindole Derivatives and Evaluation of Their Anti-Inflammatory and Anti-Microbial Activity. Pharma Innovation 2013;2(5):41-50.