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Vol. 2, Issue 4 (2013)

Diagnostic Significance of Cytogenetic Markers of Asthma in Children

Ludmyla Lytvynets
Research of cytogenetic features of the kariotype in children with bronchial asthma was conducted by studying specimens of prometaphase chromosomes of peripheral blood lymphocytes. We analyzed associations of acrocentral number of chromosomes, karyotype features. The study involved 82 children aged 6 to 18 years with asthma of varying degrees of its control over the outcome of asthma control test. Children with uncontrolled asthma received significantly higher rate of chromosome acrocentral associations 13-15 (DD), 21-22 (GG) and 13-15 - 21-22 (DG). In patients with asthma we observed a lower mitotic activity compared with that in healthy ones (PN <0,05), and with a lower degree of controllability it decreased.
Pages: 46-49  |  1705 Views  87 Downloads

The Pharma Innovation Journal
How to cite this article:
Ludmyla Lytvynets. Diagnostic Significance of Cytogenetic Markers of Asthma in Children. Pharma Innovation 2013;2(4):46-49.

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