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Vol. 1, Issue 11 (2013)

Synthesis, Characterization And Evaluation For Anticonvulsant Activity Of Acetylnaphthalene and Substituted Acetylenaphthalene Derivative Of Heterocyclic Compounds

Author(s):
Sunil Kumar, D. P. Pathak
Abstract:
A series of acetylnaphthalene and substituted acetylnaphtahlene have been prepared by mannich reaction with four different secondary amine compounds and formandehyde. In this reaction Acetyl gruoup of acetyl naphthalene and substituted acetylnaphthalene have been used as hydrogen active compound. The structures of new compounds have been confirmed by spectral data. The novel compounds were tested for anticonvulsant activity using pentylenetetrazole (scPTZ) test. Among the tested some acetylnaphthalene and substituted acetyl naphthalene derivatives of heterocyclic compounds were show significant anticonvulsant activity.
Pages: 90-101  |  997 Views  9 Downloads
How to cite this article:
Sunil Kumar, D. P. Pathak. Synthesis, Characterization And Evaluation For Anticonvulsant Activity Of Acetylnaphthalene and Substituted Acetylenaphthalene Derivative Of Heterocyclic Compounds. Pharma Innovation 2013;1(11):90-101.
The Pharma Innovation Journal