Vol. 1, Issue 8 (2012)

Author(s):
Arijit Gandhi

Abstract:
Mouth dissolving tablets (MDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients. The popularity and usefulness of the formulation resulted in development of several MDT technologies. This review describes the various formulation aspects and technologies developed for MDTs, along with various excipients, evaluation tests, marketed formulations of MDTs. There are multiple fast-dissolving OTC and Rx products on the market , most of which have been launched in the past 3 to 4 years. There have also been significant increases in the number of new chemical entities under development using a fast-dissolving drug delivery technology. Thus, in future, it is expected that this delivery system will get much importance as that of conventional delivery systems.