Vol. 1, Issue 10 (2012)

Author(s):
Ramanath K, G Bhargavi

Abstract:
Introduction: The aim of the test was to find out the antibacterial efficacy of Curcuma longa extracts on pathogens responsible for wound infections. Methodology: Rhizome extracts was prepared by soxhalation procedures. Alcoholicextract of the Curcuma longa was tested against 20 each clinical strains of Staphylococcus aureus Escherichia coli and Pseudomonas aeruginosa obtained from wound infections by disc diffusion assay. Standard strains and standard drugs were run in parallel. Results: The alcoholic rhizome extracts of Curcuma Longa showed maximum antibacterial activity against the isolates of Pseudomonas aeruginosa and Escherichia coli. The Gram positive organisms showed diminished sensitivity against alcoholic extracts of Curcuma longarhizome extract. Conclusion: The present study reveals the strong antibacterial potential of the Curcuma longa extracts on the gram negative pathogens of wound infection. The topical application of the preparation can be used as potential agents for the control of the antibiotic resistant strains of the wound colonizing and infecting pathogens