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Vol. 1, Issue 1 (2012)

A rare case of squamous cell carcinoma in an infected epidermoid cyst

Dr. Boddula NagaBhushanam
History and Examination: A 70-year man presented to the General Surgery OPD with the complaint of painless swelling on the right thigh since 2 months. On examination a solitary, round, 10 x 10 cm swelling was noted on the right upper thigh which is non-tender, firm in consistency and with restricted mobility.
Management: Ultra sonogram reveled a well-defined heterogeneous lesion of 8.2 × 7.3 cm on the medial aspect of right upper thigh which was suggestive of either infective etiology or a soft tissue neoplasm. Cytological features were suggestive of infected epidermoid cyst. Lesion was excised with clear margins and intact cyst wall.
Histopathology: Sections showed stratified squamous epithelium with full thickness anaplasia, islands of anaplastic tissue dipping down into the cyst cavity forming sheets of large pleomorphic cells with hyperchromatic nuclei. Well-formed malignant pearls were seen suggestive of squamous cell carcinoma.
Conclusion: Squamous cell carcinoma arising from the epidermal cyst can mimic that of an infected epidermal cyst. In a case of epidermoid cyst, comprehensive pathological search for malignancy is recommended when there is a rapid growth, rare site of origin, overlying skin changes and recurrent infection which is non responsive to medical therapy.
Pages: 120-125  |  46 Views  22 Downloads

The Pharma Innovation Journal
How to cite this article:
Dr. Boddula NagaBhushanam. A rare case of squamous cell carcinoma in an infected epidermoid cyst. Pharma Innovation 2012;1(1):120-125.

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