Vol. 1, Issue 1 (2012)

Background and objectives: The purpose of this study is to compare the intraoperative Fentanyl dose given to the study group with that given to the control group within the designated study population. In order to differentiate between the two groups with respect to the amount of Fentanyl that was supplied intraoperatively. Quantification of postoperative pain experienced by both the experimental and control groups. Research and control group rescue analgesic needs estimation in the postoperative care unit. In order to document the perioperative complications experienced by both the experimental and control groups. Estimating the time needed for extubation in both the study group and the control group.

Material and Methods: A study was conducted in the Department of Anesthesiology, Konaseema Institute of Medical Sciences & Research, Amalapuram, Andhra Pradesh, from January 2011 to December 2011. The study was prospective comparative randomized and involved obtaining informed consent from patients. The study included females aged 18-60 years who underwent mastectomy surgery under general anesthesia.

Results: The study conducted a statistical analysis to assess the impact of intraoperative fentanyl dosage based on hemodynamic and superficial percutaneous index (SPI) parameters. The study aimed to assess the correlation between various dosages of fentanyl and the following parameters: age, body mass index (BMI), cardiovascular health, spectral entropy, intraoperative and postoperative events and symptoms, as well as mean extubation time during mastectomy.

Conclusion: The study concludes that mastectomy performed under general anesthesia yields superior hemodynamic stability in the SPI guided group, leading to a reduced need for intraoperative fentanyl. Additionally, the study found that there was a positive analgesic effect and a reduced likelihood of postoperative nausea and vomiting compared to the trial conducted using conventional hemodynamic guidance.