Vol. 9, Issue 1 (2020)

Author(s):
Svitlana Marchyshyn, Olha Skrynchuk, Liliia Budniak and Liudmyla Mosula

Abstract:
An in-depth phytochemical study of Crambe cordifolia Steven and Crambe koktebelica (Junge) N. raw materials as sources of biologically active substances of phenolic nature is an urgent task of modern pharmacy. Therefore, the purpose of the research was to study the composition of phenolic compounds of the studied plant species. The qualitative composition and quantitative content of the phenolic compounds in Crambe cordifolia Steven and Crambe koktebelica (Junge) N. leaves were determined by HPLC analysis on Agilent 1200 chromatograph. The quantitative content of the following individual phenolic compounds was identified and established: сhlorogenic, ferulic, сaffeic, p-coumaric, syringic, sinapic, cinnamic, hydroxyphenylacetic and quinic acid, neohesperidin, rutin, quercetin-3-D-glucoside and luteolin. In Crambe cordifolia Steven leaves prevails among certain neohesperidin (1676.71 µg/g), серед hydroxycinnamic acids – сaffeic (218.43 µg/g) and chlorogenic (144,11 µg/g). A significant content of chlorogenic acid (547.62 µg/g), ferulic acid (267.71 µg/g) and neohesperidin (1809.44 µg/g) was determined in Crambe koktebelica (Junge) N.