Vol. 8, Issue 8 (2019)
Effect of supra-nutritional supplementation of vitamin E and/or selenium on oxidant-antioxidant profile in transition dairy cows
Ambily TR, Beena V, Karthiayini K, Ramnath V, Uma R, Siddaramesh A S and Sunanda C
Transition period in dairy cow is associated with oxidative stress resulting from augmented metabolic demands. The study was conducted to assess and compare the changes in oxidative stress parameters during transition period in dairy cows, supplemented with/without antioxidants; vitamin E and/or selenium. Twenty four healthy pregnant dairy cows belonging to 2nd/3rd parity at 220th day of pregnancy were selected and divided randomly into four groups of six animals each, G0 (control), G1 (selenium @ 0.3 ppm/kg DM/day), G2 (vitamin E @ 1000 IU/day) and G3 (selenium @ 0.3 ppm/kg DM + vitamin E @ 1000 IU per day). The animals were maintained on uniform standard diet plan with specific supplementation as mentioned and uniform THI (average THI 79) during the entire study period (from 220th day of pregnancy to 30 days post-partum). Blood and serum samples were collected on 220th & 250th days of pregnancy, the day of calving and on the 30th day post-partum. Oxidative stress parameters (blood Glutathione peroxidase and Superoxide dismutase; serum catalase and malonaldehyde) haematological parameters (volume of packed red cells-VPRC, total erythrocyte count-TEC, haemoglobin concentration-Hb and total leucocyte count-TLC and serum biochemical parameters (total protein, albumin, globulin and albumin: globulin ratio) were estimated. We observed oxidative stress in G0 and better antioxidant status in the supplemented groups on the day of calving and 30th day post-partum. The improvement in health status of supplemented group animals was evident from better oxidant-antioxidant and Hemato-biochemical profile. Thus based on this study supplementation of vitamin E/selenium may be recommended beneficial for dairy cows, as it alleviates oxidative stress and provide improved health status during transition period.
How to cite this article:
Ambily TR, Beena V, Karthiayini K, Ramnath V, Uma R, Siddaramesh A S and Sunanda C. Effect of supra-nutritional supplementation of vitamin E and/or selenium on oxidant-antioxidant profile in transition dairy cows. The Pharma Innovation Journal. 2019; 8(8): 97-106.