Vol. 8, Issue 4 (2019)
A novel approach for topical delivery using emulgel
Rajesh Akki, B Susmitha and J Kiranmai
Many advantages of gels which are having a major limitation is the delivery of hydrophobic drugs. So, this limitation can be overcome by using an emulsion based approach where even a hydrophobic moiety can enjoy the unique property of gels. The combination of both gel and emulsion is referred as Emulgel. In recent years, there has been great interest in the use of novel polymers. A unique aspect of dermatological preparations is the direct accessibility of the skin as a target organ for the diagnosis and treatment. The combination of hydrophilic cornified cells in hydrophobic intercellular material provides a barrier for both hydrophilic as well as hydrophobic substances. Within the major group of semisolid preparations, the use of transparent gels has expanded both in pharmaceutical and cosmetic preparations. Polymer has a dual action which can function as emulsifier and thickeners because of gelling capacity of these compounds allows the formulation of stable emulsion and cream by decreasing the interfacial tension and surface area and at the mean while increasing the viscosity of the aqueous phase. In fact the gelling phase in the water phase converts the classical emulsion into emulgel. These emulgels are having major advantages on vesicular as well as on conventional systems in many aspects. Various penetration enhancers can potentiate the effect, hence emulgels can be used as better topical drug delivery systems over present drug delivery systems. The use of emulgel can be extended in analgesics and antifungal drugs.
How to cite this article:
Rajesh Akki, B Susmitha and J Kiranmai. . The Pharma Innovation Journal. 2019; 8(4): 35-42.