Vol. 8, Issue 12 (2019)

Author(s):
P Sailaja Rao and Pingili Divya

Abstract:
Crohn’s disease (CD), characterized as inflammatory bowel disease (IBD), is a chronic disease that affects the lining of digestive tract and includes lifelong therapy. High incidence of this disease is witnessed in western countries like USA, Canada, UK and is slightly apprehending in Asian countries. Medical treatments for IBD are restricted and were aimed at bestowing symptomatic amelioration. When conventional treatments are not responding in patients suffering from Crohn’s disease, chemotherapy with drugs like infliximab, adalimumab, methotrexate, and cyclophosphamide may aid in treating the symptoms and inclines the disease into remission. Though medication is helping out in the maintenance of Crohn’s, the lifestyle improvement can support in the better management of the disease. An improved perceptive of pathological mechanisms endeavors new castles in air for tailored therapies. In the present review, emphasis was laid on portrayal of pathological mechanisms, newer diagnostic techniques, chemotherapy and the prominence of diet, exercise, yoga and pranayama in the remission of Crohn’s disease.