Vol. 7, Issue 5 (2018)

Author(s):
Mushtaq Ahmad Malik, Showkat Ahmad Bhat, Muneeb Ur Rehman, Showket Sidique, Zubair Ahmad Akhoon, Purnima Shrivastava and Sheikh Bilal Ahmad

Abstract:
The present study was under taken to investigate the presence of phytochemical constituents in aqueous and methanol extracts of rhizomes of Rheum emodi and to investigate their antibacterial activity. The estimation of phytochemical constituents in methanol proved to be effective solvent for the extraction of secondary metabolites from the rhizomes of Rheum emodi. Methanol extract exhibited significantly higher (p<0.05) amounts of secondary metabolites and antibacterial activity against the test organisms at 10mg/ml, 36.7 ± 0.19 and 39.6 ± 0.23 in comparison to standard antibiotics 19.8 ± 0.16 and 19.9 ± 0.21 and aqueous extract and 21.7 ± 0.14 and 18.6 ± 0.15. The methanol extract also exhibited higher zone of inhibition against bacteria from 9-12 mm while aqueous extract showed zone of inhibition from 8-11mm.