Vol. 7, Issue 4 (2018)

Author(s):
VVV Amruth Kumar, K Nalini Kumari, K Satish Kumar, V Gireesh Kumar and M Lakshman

Abstract:
Clinical, hematological and biochemical parameters were evaluated in the dogs suffering with Transmissible Venereal Tumors that were treated with Inj Vincristine complete alleviation of clinical signs was noticed in 17 dogs (85%) by day 21 (week days after third dose), the fourth dose was also administered in these dogs to rule out the minimal presence of TVT cells. Hematological parameters like Hb, PCV, TEC and leucocytes had significantly declined (P<0.05) from day 0 to day 28. Serum biochemical parameters like BUN, Serum Creatinine, ALT, AST and ALP showed significant increase during chemotherapy.