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Vol. 7, Issue 4 (2018)

Foot-and-mouth disease and vaccination

Author(s):
Vishweshwar Kumar Ganji, Mallesh Pottabathula, Sampath Kontham and Pruthvi Raj Boga
Abstract:
Foot and mouth disease is an infectious and highly contagious viral disease of domestic and wild cloven-hoofed animals. Vaccination is a major means to control FMD in most endemic areas. Current FMD vaccines are typically produced by inactivation of cell culture virus with binary ethylenimine and formulated with oil adjuvant. This vaccine has a subset of limitations such as requirement for frequent booster doses, poor cellular response, improper inactivation of virus. The focus has been shifted for production of an alternative, more desirable vaccine formulations like live attenuated vaccines, live vectored vaccines, DNA vaccines, subunit vaccines, virus like particles etc., which are achieved through rDNA technology.
Pages: 01-03  |  369 Views  76 Downloads
How to cite this article:
Vishweshwar Kumar Ganji, Mallesh Pottabathula, Sampath Kontham and Pruthvi Raj Boga. Foot-and-mouth disease and vaccination. 2018; 7(4): 01-03.
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