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Vol. 5, Issue 9 (2016)

Evaluation of sensitivity and specificity of immunochromatographic test for detection of malaria parasites P. falciparum / P. vivax in Sudan

Author(s):
Budoor M Alnoaemi, Sulafa I Mohammed, Nora H Sayedahmed, Al-Husein M Chyad and Mohamed A Hussain
Abstract:
Malaria diagnosis has received special interest from the researchers worldwide due to the challenges that faced Malaria control as the diagnosis considered the corner stone in malaria control. To counteract the drawbacks of the traditional methods used in malaria diagnosis, Immunochromatographic test has been extensively used nowadays. In this study we aimed to evaluate the sensitivity and specificity of Immunochromatographic test for detection of Malaria (P. falciparum / P. vivax) in patients with presumptive clinical diagnosis of Malaria in Sudan.
387 blood samples were tested using Immunochromatographic test and microscopic test, we found that 200 samples were negative, and 187 were positive. We used expert lab technicians who were blinded to the Immunochromatographic test result to prevent bias.
The overall sensitivity test of Immunochromatographic test was 98.91%, which is considered slightly low compared to the sensitivity value mentioned by the manufacturer (99.7%), but it is acceptable to detect P. falciparum parasitemia at densities of (11-100 parasite/100 field) and (1-10 parasites/field). The overall specificity was 67.45% which is very low compared to the specificity value mentioned by the manufacturer (99.3%). Therefore, Immunochromatographic test available in Sudan should be considered as a supportive tool to microscope in the diagnosis of Malaria and it can be used when the microscope is not available or guaranteed.
Pages: 20-22  |  677 Views  27 Downloads
How to cite this article:
Budoor M Alnoaemi, Sulafa I Mohammed, Nora H Sayedahmed, Al-Husein M Chyad and Mohamed A Hussain. Evaluation of sensitivity and specificity of immunochromatographic test for detection of malaria parasites P. falciparum / P. vivax in Sudan. 2016; 5(9): 20-22.
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