Vol. 4, Issue 1 (2015)
Differential Access to Treating Of Drug-Induced Hepatotoxicity in Patients with Chronic Lymphocytic Leukemia
In this article abilities of differential administration of hepatoprotective medications are observed regarding a type of drug-induced liver injury during chemotherapy in patients with chronic lymphocytic leukemia. The type of drug-induced liver injury was determined depending on the grade of increasing of aminotransferase and alkaline phosphatase levels. Effectiveness of arginine glutamate at presence of cytolitic type of drug-induced liver injury and ursosan at presence of cholestatic type of drug-induced liver injury was studied. It was determined that including of these medicines in basic therapy of drug-induced liver injury promotes normalization of biochemical indexes that characterize functional state of liver parenchyma and enables to provide chemotherapy courses of chronic lymphocytic leukemia completely.
How to cite this article:
Grydguk T.І.. Differential Access to Treating Of Drug-Induced Hepatotoxicity in Patients with Chronic Lymphocytic Leukemia. The Pharma Innovation Journal. 2015; 4(1): 17-20.