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Vol. 2, Issue 4 (2013)

Synthesis, characterization and Screening of 1,2,4 Triazole Derivative Compounds for Its Antimicrobial Activity

Author(s):
Sushma Dev, Dr Ramesh Bodla
Abstract:
A series of 3-benzoylsulfanyl derivatives of 4-methyl-1,2,4-triazole were synthesized by acylation of starting triazole-3-thiol with appropriately substituted benzoyl halide. All members of the set were evaluated for in vitro antimicobacterial activity againstPsuedomonas aerogenosaEscherichia coliBacillus subtilisBacillus pumitis and antifungal acivity against A. niger, C. albicans. The activities were expressed as the minimum inhibitory concentration. The compound exhibited only a moderate or slight antimycobacterial activity. The structures of the newly synthesized compounds were characterized by IR, 1H NMR and elemental analysis.
Antifungal activity Chart
Fig.: Antifungal activity Chart
Pages: 54-60  |  618 Views  6 Downloads
How to cite this article:
Sushma Dev, Dr Ramesh Bodla. Synthesis, characterization and Screening of 1,2,4 Triazole Derivative Compounds for Its Antimicrobial Activity. 2013; 2(4): 54-60.
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