Volume 3, Issue 2


Dynamics of connective tissue metabolism and NO-Synthesizing function during patients’ treatment with carnitine containing drugs after myocardial infarction


Author: Jaroslava Vandzhura *

Abstract: The article presents data on the effect of carnitine containing drug cardonat on endothelial dysfunction and pathological stroma restructuring of myocardium in patients after myocardial infarction within 6 months of medical rehabilitation.
Combination of cardonat with standard therapy promotes correction of collagen metabolism abnormalities, namely reducing the synthesis of abnormal collagen.
Also, this drug combination improves endothelial function: it increases the synthesis of nitric oxide, reduces the level of active nitrogen radicals. This generally provides a favourable clinical course of postinfarction period and reduces the pathological left ventricle remodelling.


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