Volume 2, Issue 3


Transdermal Patch of Anti-Diabetic Drug


Author: Mayank P. Patel*, M. M. Gupta
Department of Pharmaceutics, Jaipur College of Pharmacy, Jaipur (Rajasthan) India.

Abstract: In the present work, monolithic matrix transdermal systems containing Drug x were prepared using various ratios of the polymer blends of hydroxy propyl methyl cellulose (HPMC) and Eudragit S 100 (ES) with triethyl citrate as a plasticizer. A 32 full factorial design was employed. The concentration of HPMC and ES were used as independent variables, while percentage drug release was selected as dependent variable. Physical evaluation was performed such as moisture content, moisture uptake, tensile strength, flatness and folding endurance.

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