Volume 2, Issue 2


Antioxidant and Cytotoxic Activities of Methanol Extract of Urena lobata (L) Leaves


Author: Md. Sekendar Ali*, Kazi Omar Faruq, Md. Aziz Abdur Rahman, Md. Aslam Hossain Department of Pharmacy, International Islamic University Chittagong, Bangladesh.

Abstract: The methanol extract of leaves of Urena lobata (L) (Malvaceae) has been selected to determine the antioxidant and cytotoxic potentials. The crude extract were tested for in vitro free radical scavenging assays such as 1, 1 diphenyl-2-picryl-hydrazyl (DPPH). Total phenolic and flavonoids content of U. lobata were analyzed. The sample effectively scavenged free radical at all different concentrations and showed potent antioxidant activity. Finally cytotoxic activity has been assayed using brine shrimp lethality bioassay where vincristine sulphate was used as standard. The antoxidant results were compared with standard antioxidant such as ascorbic acid and quercetin. The whole study shows that the crude methanol leaves-extract has potent antioxidant and cytotoxic activities.

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