Volume 2, Issue 2
Migraine-A Complete Review
Author: B.Kumaraswamy, V. Madhu Latha, A.V.Bhanu keerthi, P. Sri Divya, M.D. Dhana Raju, S.Ramachandran
Department of Pharmacology, GIET School of Pharmacy, Rajahmundry, Andhra Pradesh, India.
Abstract: Migraine is a mysterious disorder characterized by pulsating headache, usually restricted to one side, appearing in the form of attacks lasting from 4-48 hrs which is characterized by altered bodily perceptions, severe headache, nausea, vomiting and sensitivity to light. Pulsate dilation of large cranial vessels is the immediate cause of pain. Impulses from the cortex, thalamus and hypothalamus activate the migraine centre responsible for generation of migraine attacks, putatively located in the brain stem. Two types of migraines are seen generally-classical migraine (a migraine with an aura or warning) and common migraine (migraine without an aura). Less common migraines are abdominal migraine, basilar migraine, cyclic migraine, hemiplegic migraine, nocturnal migraine, ophthalmic and pregnancy migraine. These can be diagnosed by the symptoms like intense headache, relentless throbbing pain, inability to carry out daily activities etc. Patients suffering with worst headaches associated with nervous system symptoms like visual, sensory or hearing losses require additional tests like blood test, brain scan (CT scan), spinal tap etc. One can get relief by allopathic and ayurvedic medications. Home remedies are also known to retard mild migraines. The frequency, severity of attacks and response of individuals and their sensitivity to drugs determine the choice of drug therapy.
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