Volume 2, Issue 10


Gamma Glutamyltransferase Levels and Its Association with High Sensitive C - reactive protein in Sudanese Patients with Type 2 Diabetes Mellitus


Author: Mohamed Arbab*, Haala Gabra, Elmutuz Elssaig, Hani Fahmi

Abstract: The aim of the study is to examine the relationship between Gamma-glutamyltransferase and the marker of inflammation, i.e., high sensitive C reactive protein, in type 2 diabetic patients in Sudan.
Materials and Methods: A prospective, analytical, hospital based, case control study was carried out Fedail Hospital and Khartoum Teaching Hospital. 100 patients (50 males and 50 females) presenting with type 2 Diabetes Mellitus were enrolled in this study compared to and 50 healthy control subjects from May 2012 to May 2013 were included in the study. Fasting blood glucose, Serum gamma-glutamyltransferase and High sensitive C-reactive protein were measured.
Results: A significant positive correlation between Gamma Glutamyltransferase and high sensitivity-C-reactive protein in patients with type 2 diabetes (r = 0.431, p <0.001).
Conclusion: These results suggested that high sensitivity-C-reactive protein levels increase continuously across the fasting blood glucose spectrum starting from the lowest fasting blood glucose in both men and women.

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