Volume 2, Issue 1

 

In vitro Cytotoxic Activity of Methanolic Extract of M. pachycarpa (Benth) Leaves

 

Authors: Mohammed Abdullah Jainul , Shofiul Azam *, Amin Chowdhury
Department of Pharmacy, International Islamic University Chittagong, Chittagong-4203, Bangladesh

Abstract: Millettia pachycarpa belongs to the family Fabaceae, a perennial climbing shrub belonging to the genus Millettia. The present investigation evaluates the cytotoxic activity of methanolic extract of M. pachycarpa  Benth leaf. Brine shrimp lethality bioassay method is used to assess the cytotoxic activity of M. pachycarpa  Benth. The laboratory studies show that brine shrimp bioassay method the LC50 value of methanolic extract of  M. pachycarpa leaf  is 1.7493 µg/ml  with a 95% confidence limit[1] of  1.3679-2.2370 µg/ml.

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