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Vol. 12, Special Issue 7 (2023)

Histocompatibility influence, vulnerability and immunity to RSV infection of layer (CARI-Priya) chicken

Author(s):
Tuhin Ray, JK Chatterjee, SK Mukhopadhayay, RN Hansda, S Mondal, S Pradhan, Rakibul Hoque and Stephen Soren
Abstract:
We examined the influence of histocompatibility on the outcome of infection of Layer CARI-Priya strain with Rous Sarcoma Virus (RSV). Before inoculation, we conducted genomic analysis of the virus using ALV AE(326bp), ALV A(229bp), and MDV(583bp) primers. The introduction of RSV-A into CARI-Priya chicks resulted in the development of tumours with progressive or regressive phenotypes, exhibiting varying tumour profile index (TPI). A considerable increase in TPI scores (5 or 6) in a subset of chicks revealed their vulnerability to RSV-A. 90% of the chicks had metastatic disease, which was a mixture of Myxosarcoma and fibro sarcoma.
Pages: 1129-1137  |  236 Views  107 Downloads
How to cite this article:
Tuhin Ray, JK Chatterjee, SK Mukhopadhayay, RN Hansda, S Mondal, S Pradhan, Rakibul Hoque and Stephen Soren. Histocompatibility influence, vulnerability and immunity to RSV infection of layer (CARI-Priya) chicken. The Pharma Innovation Journal. 2023; 12(7S): 1129-1137.

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