Vol. 11, Special Issue 9 (2022)

Author(s):
Ravi P Goyal, Anil K Gangwar, Sangeeta D Khangembam, Vipin K Yadav, Yogendra Singh and Prafull Kumar

Abstract:
Caprine periosteum was decellularized with 5% Sapindus mukorossi and 1.5 cm of radial bone defect in New Zealand White rabbits was created in 2 groups of 6 rabbits in each. Scaffold in group I (control) and group II (treated with bone marrow stem cells) compared for fracture healing efficiency. Radiographically, at 12 weeks, there was newly formed bone in the bone defect site in group II only. Histologically, Group II showed woven bone formation which was evident of bone healing. Group II showed no significant difference in ALP.