Vol. 10, Special Issue 5 (2021)

Author(s):
RKR Sangamitra, G Suganya, V Leela and M Balagangadhara Thilagar

Abstract:
The study was conducted to estimate the fibrinogen concentration in dogs affected with parenchymal, biliary and neoplastic hepatic disorders compared with dogs which are apparently healthy. Twenty apparently healthy dogs formed the control group. Twenty dogs in which 9 dogs formed the parenchymal disorder, six dogs with biliary disorder and five dogs with neoplastic disorder based on ultrasonographic investigation formed the experimental group. Since liver is major site for the synthesis and removal of thermoelastographic proteins, the present study was framed to measure the concentration of fibrinogen in healthy as well as dogs with various hepatic dysfunction. The fibrinogen concentration was significantly increased in dogs affected with parenchymal, biliary dysfunction and significantly reduced in dogs with neoplastic disorders of experimental group when compared with control group. Thus the results of this study conveys that there is a significant alteration in the concentration of fibrinogen in all three disorders of hepatic dysfunction dogs and it could be the cause for the haemostatic disorders in dogs.